GECLID is an interlaboratory comparisons' program for immunology labs
Biological samples within the program are usually real samples, of non-repetitive patients, who are recruited by different health centers, similar to the cases you may receive any day. GECLID has Immunologists, health professionals, who provide their experience andvision for management and workflows of the program. The head of this program since its beginning in 2011, Dr Carmen Martín, is as well an Immunologist, ready to help you with any questions related to the controls and other issues related to both quality and diagnosis .
You can enroll the program all along the year at GECLID website and -if you recorded your registration with your user-, you can recover all your data and just modify what you need in less than 2 minutes . If you are new by us or you hadn't your registration recorded last year, you can also register from the web (https://www.geclid.es/mod/feedback/view.php?id=8397 ) . Shipping schedule is also available at www.geclid.es .
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IMMUNOCHEMISTRY AND ALLERGY |
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IQ179 Immunoproteins (Igs, C3, C4, C1ihn, C1q, B Factor, RF y RCP) |
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This scheme comprises Immunoglobulins (IgG, IgA, IgM, IgE), complement (C3, C4, C1inh, C1q, B Factor ) and RCP and Rheumatoid Factor; results for B factor will be collected in the rounds ß (beta, second) and ε (epsilon, fifth). |
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IQ2 IgG subclasses |
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IgG1, IgG2, IgG3, IgG4 |
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IQ3 Specific IgE (native and recombinan allergens) |
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IgE results recognizing different allergens, including recombinant ones |
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IQ4 Serum paraproteins |
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Detection and typing of monoclonal components (Igs, light chains) in serum |
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IQ5 Urine paraproteins |
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Detection and typing of monoclonal components in urine |
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IQ6 Oligoclonal Bands |
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Detection and identification of IgG band patterns in pairs CSF-serum for the diagnosis of MS |
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IQ8 Functional complement |
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Functional capacity, hemolytic activity and inhibitor C1 activity aimed at the diagnosis of HAE |
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IQ11 Response to vaccination |
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Antibodies in response to vaccines |
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IQ14 IFN Production in response to pathogens |
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IGRAS, interferon gamma release assays |
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IQ15 Anti TNF therapy monitoring |
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Detection and analysis of anti-TNF drugs (etanercept, adalimumab, infliximab) and antibodies |
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IQ16 Soluble CD25 |
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Detection and (semi) quantitative analysis of soluble CD25 in serum |
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CELL IMMUNITY |
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This is a joint quality control of the Iberian Society of Cytometry and the Spanish Society of Immunology |
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IC1 Lymphocytes |
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% and count of lymphocytes T, B & NK |
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IC2 Stem Cells |
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Counts and% of viable CD34 + and CD45 + populations |
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IC3 Residual leukocytes |
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Leukocyte count in leukoreduced blood products for quality control |
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IC48 Immunophenotype (Leukemia / Lymphoma) and M.R.D. |
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Lineage, stage and diagnosis of leukemia and MRD by flow cytometry |
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IC5 Lymphocyte function |
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Included in this scheme are tests for lymphocyte proliferation in response to mitogens and the production of ATP by CD4 + in response to PHA |
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IC6 Innate function |
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Oxidative burst and phagocytosis |
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IC7 Molecular diagnosis of Leukemia |
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Clonality T / B, BCR / ABL p210 and p190, PML-RARA, FLT3 ITD and ITK, rearrangements of IgH and TCR, mutations in the CALR, MPL and JAK exon 12 |
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IC9 Anti-CD20 therapy (rituximab) monitoring |
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High sensibility detection and count of B cell populations (memory, plasmablasts...) |
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AUTOINMMUNITY |
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AU1 Autoantibodies related to hepatic and gastric pathologies |
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Anti gastric parietal cells (GPA), AMA, ASMA, LC-1, LKM |
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AU2 Antinuclear antibodies - ANAs |
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ANAs, ENAs and related |
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AU3 Anti-Thyroid antibodies |
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In this scheme you can compare your results for antibodies Anti TSH receptor ;Anti thyroperoxidase (TPO) and Anti thyroglobulin (TGB) |
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AU5 Diabetes related antibodies |
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ICAs, anti GAD, anti-IA2, anti-insulin (IgG and IgA) |
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AU6 Anti-Phospholipid antibodies |
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This scheme includes tests for the detection and quantification of IgG and IgM anticardiolipin and anti-ß2 glycoprotein I. |
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AU7 ANCAs and GBM (related antibodies) |
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p-ANCA, c-ANCA, x-ANCA, MPO, PR3, MBG, elastase, lactoferrin |
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AU8 Coeliac Disease related antibodies |
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EMAs, deamidated gliadin,tisular anti-transglutaminase, IgG and IgA |
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AU9 Anti Cyclic Citrullinated Peptides Antibodies |
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anti CCP |
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AU16 Antineuronal antibodies |
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anti Hu, Ri, Yo, Ta, Ma, in paraneoplastic syndromes |
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AU17 Anti Phospholipase A2 receptor antibodies |
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Anti RPLA2, |
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AU18 Calprotectin |
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Fecal Calprotectin, in IBD |
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AU22 Autoimmunity Cases (IFI Images) |
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Pattern idetification on IIF images with clinical data. Educational Scheme |
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HISTOCOMPATIBILITY AND IMMUNOGENETICS |
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HLA1 Serological typing of HLA |
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Serological typing, class I HLA |
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HLA2 Disease-related HLA |
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HLA B-27 |
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HLA-B*57:01 |
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Coeliac Disease related HLA |
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HLA3 Crossmatch |
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Crossmatch by CDC and flow cytometry |
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HLA4 Anti-HLA Antibodies |
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anti HLA: CDC, screening and single antigen identification of anti-class I and class II HLA antibodies |
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HLA5 Low Resolution DNA-based HLA typing (class I and II) |
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Low resolution typing of loci HLA-A, HLA-B (and HLA-C as an option), HLA-DRB1(optional: HLA-DRB3, HLA-DRB4, HLA-DRB5,HLA-DQA1, HLA-DQB1) |
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HLA6 High resolution HLA DNA typing (class I and II) |
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High resolution typing of loci HLA-A, HLA-B (and HLA-C as an option), HLA-DRB1(optional: HLA-DRB3, HLA-DRB4, HLA-DRB5,HLA-DQA1, HLA-DQB1, HLA-DPA1, HLA-DPB1). |
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HLA8 Chimerism |
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Chimerism assays on blood mixtures |
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HLA9 KIR Typing |
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2DL1, 2DL2, 2DL3 , 2DL4 , 2DL5 , 2DS1 , 2DS2 , 2DS3 , |
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2DS4 , 2DS5 , 2DP1 , 3DL1 , 3DL2 , 3DL3 , 3DS1 , 3DP1 |
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HLA11A HPA typing |
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Plaquetary antigen typing HPA (1,2,5,15) |
